Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

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Administrative data

First-aid measures

Description of first aid measures:
General advice: Take the victim out of the contaminated area. Remove contaminated clothing immediately and dispose of safely.
If inhaled: Move to fresh air. Make the victim blow his nose. Seek medical advice.
In case of skin contact: Rinse immediately with plenty of water for at least 15 minutes. Seek medical advice.
In case of eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Seek medical advice.
If swallowed: Do not induce vomiting. Make the victim rinse his mouth with water. Seek medical advice.

Most important symptoms and effects, both acute and delayed
Symptoms: Nausea.

Indication of any immediate medical attention and special treatment needed
Treatment: No data available. Treat symptomatically.

Fire-fighting measures

Extinguishing media:
Suitable extinguishing media: All means (e.g. water, carbon dioxide, dry chemical extinguisher).
Unsuitable extinguishing media: Strong water jet.

Special hazards arising from the substance or mixture:
In case of fire, the product may emit toxic and/or irritating fumes.
Supposed thermal decomposition/oxidation:
Carbon monoxide and carbon dioxide

Advice for firefighters:
Special protective equipment: Use self-contained breathing apparatus. Wear full protective suit.
Further information: Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Avoid discharging extinguishing water in the environment.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:
Particle full face respirator or powered air purifying respirator. Suitable gloves. Dedicated work clothes.

Environmental precautions:
Avoid any spreading of the product.

Methods and materials for containment and cleaning up:
General advice: Sweep and shovel the solid product into a container specially adapted for its recovery or destroying (avoiding dust formation). Close and label thoroughly.
Cleaning of contaminated zone: After cleaning up the product, rinse the polluted area with water.
Elimination of recovered materials: Deliver to the Environmental service of the factory or to any specialized and approved disposal company.

Reference to other sections:
Additional advice: Evacuation of area and intervention of special services recommended.

Handling and storage

Precautions for safe handling:
Advice on safe handling (industrialscale): Local ventilation and emission point dust extraction. Enclosed transfer recommended.
Take precautionary measures against electrostatic loading. Earth vessels and equipment well.
Advice on safe handling(laboratory scale): Handling in a hood.

Conditions for safe storage, including any incompatibilities:
Requirements for storage rooms and vessels: Keep in a cool, well-ventilated place.
Advice on common storage: Keep away from chemicals as it is a pharmaceutical substance
Further information on storageconditions: Keep in a well closed container, away from moisture and light.
Storage temperature : Keep at ambient temperature.
Advised packaging material: Glass, polythene.
Sensitivity
Humidity : Sensitive to moisture.

Specific end use(s):

Transport information

Land transport (ADR/RID)

UN number:
3077
Shippingopen allclose all
Class:
9
Packaging group:
III
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Marine transport (IMDG)

UN number:
3077
Proper shipping name and description:
Environmentally hazardous substance, solid, n.o.s.
Chemical name:
CANRENONE
Class:
9
Packaging group:
III
Marine pollutant
Remarksopen allclose all

Air transport ICAO/IATA

UN number:
3077
Proper shipping name and description:
Environmentally hazardous substance, solid, n.o.s.
(CANRENONE)
Chemical name:
CANRENONE
Class:
9
Packaging group:
III
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Exposure controls / personal protection

Personal protection equipment
(IMPORTANT: to be adapted following the workplace risk assessment.)
Special recommendations: Pregnant women, seek medical advice before handling.

Industrial workplace
Respiratory protection: Particle full face mask or powered-air purifying respirator.
Hand protection: Suitable gloves.
Glove material : Nitrile rubber
Layer thickness : 0,11 mm
Break through time: > 480 min
Eye/face protection: See respiratory protection.
Body Protection: Dedicated working clothes recommended.
Hygiene measures: Wash hands.

Laboratory
Respiratory protection: Handling in a hood.
Hand protection: Suitable gloves.
Eye/face protection: Safety glasses.
Body Protection: Working clothes.
Hygiene measures: Wash hands.

Stability and reactivity

Safety remarks: Risk of dust explosion.
Reactivity: No data available.
Chemical stability: No data available.
Possibility of hazardous reactions: No data available.
Conditions to avoid: No data available.
Incompatible materials: Strong oxidizing agents.
Hazardous decompositionproducts: Supposed thermal decomposition/oxidation:
Carbon monoxide and carbon dioxide
Sanofi hazard bands-Safety : SHB 4 (preliminary)
Further information see chapter 16.

Disposal considerations

Waste treatment methods:
Product: Deliver to the Environmental service of the factory or to any specialized and approved disposal service.
Uncleaned packaging: Deliver to the Environmental service of the factory or to any specialized and approved disposal service.