Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 March 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study conducted in accordance with generally accepted scientific principles, possibly with incomplete reporting or methodological deficiencies, which do not affect the quality of the relevant results.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubility
Water solubility:
109 mg/L
Remarks on result:
other: No information regarding pH provided in study report. Column temperature for HPLC experiment listed as ambient, however no specific value listed.
Details on results:
At 300 nm, the peak areas observed for the test substance test solutions were 5320116 and 5595645. Using these values in Equation 1 as y values and solving for x, we obtain water solubility values for the test substance of 106 mg/L and 112 mg/L.

Any other information on results incl. tables

No information regarding pH provided in study report. Column temperature for HPLC experiment listed as ambient, however no specific value listed.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
The test compound was found to have a water solubility of 109 mg/L (average of 106 mg/L and 112 mg/L).
Executive summary:

In a water solubility study (20169-45), the water solubility has been determined to be 109 mg/l of solution at ambient temperature by the flask method based on OECD Test Method 105.