Registration Dossier
Registration Dossier
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EC number: 273-794-1 | CAS number: 69029-48-7 Product from the pH-adjustment of indium-rich solutions causing the precipitation of indium, ammonium and cadmium hydroxides and sulfates and zinc sulfate.
Repeated dose toxicity: inhalation
Administrative data
- Endpoint:
- sub-chronic toxicity: inhalation
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- other: software
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
- Principles of method if other than guideline:
- STOT RE of UVCB substance was determined by classifying based on Mixture rules from EU CLP (tier 2=summation of classified components to derive Hazard class) and back calculation to the corresponding criteria
- GLP compliance:
- no
- Remarks:
- equivalent quality assurance
Test material
- Reference substance name:
- Indium, cake
- EC Number:
- 273-794-1
- EC Name:
- Indium, cake
- Cas Number:
- 69029-48-7
- IUPAC Name:
- Insoluble indium-containing residue after precipitation of indium bearing solutions
Constituent 1
Test animals
- Species:
- other: standard species relevant to acute toxicity classification
Results and discussion
Effect levels
- Remarks on result:
- not measured/tested
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
The calculated classification via additivity method resulted in an "STOT RE cat 1" classification for the UVCB substance (toxicity of all metal constituents are known from 9th ATP CLP + all assessed metals). The result is mainly driven by Pb compounds.
Applicant's summary and conclusion
- Conclusions:
- Good quality study that can be used to derive classification of the UVCB substance and predict hazard. Note toxicities of constituents/species as of 9th ATP CLP + assessed metals
- Executive summary:
The study provided a conservative estimate of the STOT RE: classification of both typical and worst case samples is STOT RE cat 1, H372.
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