Registration Dossier
Registration Dossier
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EC number: - | CAS number: 91744-35-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
NOEC = 100 mg/L (from ready biodegradation test, 67.3% biodegradation within 14 days in toxicity control)
Key value for chemical safety assessment
Additional information
No standard studies evaluating the effect of Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates (CAS No. 97593-30-1) on respiration inhibition of aquatic microorganisms are available. Therefore, a ready biodegradability study is used to derive a NOEC for this endpoint. If a compound degrades well in a ready biodegradability test, or does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value. This approach is in accordance with the Guidance on information requirements and chemical safety assessment (Chapter R.7b: Endpoint specific guidance, ECHA 2008).
A substance can be assumed to be not inhibitory of the activity of aquatic microorganisms if, in the toxicity control of a ready biodegradation test, more than 25% biodegradation occurs within a period of 14 days (OECD Guideline 301). For Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates a biodegradation screening test according to OECD 301F is available (Weyers, 2007). This test includes a toxicity control containing 100 mg/L of test material and reference substance (sodium benzoate). Within 14 days, 67.3% biodegradation took place in this toxicity control clearly indicating the lack of toxic potential of Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates to aquatic microorganisms, and therefore, the test item concentration of 100 mg/L can be used as a NOEC.
Based on the above information it is considered that Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates is not inhibitory of aquatic microorganisms activity and further testing for this endpoint is not deemed necessary.
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