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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 13, 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
method according to Siwoloboff
Key result
Boiling pt.:
101.3 °C
Atm. press.:
1 003.8 hPa
Remarks on result:
other: Average value ± standard deviation: 101.3 ± 0.06 ºC.

Table 1. The values of an initial boiling point

Sample

Boiling point, ˚C

1

101.4

2

101.3

3

101.3

Average value ± standard deviation, ˚C

101.3 ± 0.06
Conclusions:
The value of an initial boiling point of test substance was determined to be 101.3 ± 0.06˚C under atmospheric pressure of 1003.8 hPa.
Executive summary:

The boiling point of test substance was determined according to the OECD 103 Guideline and EU A.2 Method (Method according to Siwoloboff). The average value of an initial boiling point was found at approximately 101.3 ± 0.06˚C when heated at 10 ˚C per minute starting at 30 ˚C. Then at about 10.0˚C below the expected boiling temperature, the heating rate was reduced to 3 ˚C/min. The value of an initial boiling point of test substance was determined to be 101.3 ± 0.06˚C under atmospheric pressure of 1003.8 hPa.

Description of key information

Key study: Test method 103. GLP study. The value of an initial boiling point of test substance was determined to be 101.3 ± 0.06˚C under atmospheric pressure of 1003.8 hPa.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
101.3 °C

Additional information

Key study: The boiling point of test substance was determined according to OECD 103 and EU A.2 Method (Method according to Siwoloboff). The value of an initial boiling point of test substance was determined to be 101.3 ± 0.06˚C under atmospheric pressure of 1003.8 hPa.