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EC number: 471-980-9 | CAS number: 1016986-95-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing was conducted between 1st September to 10th October 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Meets the criteria for classification as Reliable without restriction according to Klimisch et al (1997)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EEC, A8 (shake-flask method)
- GLP compliance:
- yes
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- -
- EC Number:
- 471-980-9
- EC Name:
- -
- Cas Number:
- 1016986-95-0
- Molecular formula:
- Hill formula: C42 H24 Lim N9 Nan O15 S6 m+n=5 3=
- IUPAC Name:
- 7-{2-[2-(2-{5-cyano-4-methyl-2,6-bis[(4-sulfophenyl)amino]pyridin-3-yl}diazen-1-yl)-4-(naphthalen-2-yl)-1,3-thiazol-5-yl]diazen-1-yl}naphthalene-1,3,5-trisulfonic acid trilithium hydride disodium hydride
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- < -3.16
- Temp.:
- 22 °C
- pH:
- 7
Any other information on results incl. tables
Results
Preliminary estimate
Approximate solubility in n-octanol: 4.90 x 10 -3 g/l
Approximate solubility in water: >136.300 g/l
Approximate Pow< 1.3 9 x 10-5
Log10 Pow <-4.86
Definitive test
The mean peak areas or absorbances obtained for the standard, stock and sample solutions are shown in the following two tables:
Organic Phase
|
Aqueous Phase
|
The total weights (mg) and analysed concentration (mgll) of the respective phases are shown in the following table:
|
pH of n-octanol saturated water: 7.0
pH of stock solution: 7.0
Temperature: 21.6 +/- 0.5°C
The partition coefficient determined for each sample is shown in the following table:
Table 8.5
|
Mean Pow : 6.96 x 10-4, log10 Pow 3.16 Pow standard deviation : 1.9 1 x 10 -4
Linearities of the detector response with respect to concentration were assessed over the nominal concentration range of 0 to 2 mg/l for the organic phase and 0 to 300 mgll for the aqueous phase.
These were satisfactory with correlation coefficients of 1.000 and 0.999 being obtained.
Discussion
Substances having a log10 Pow of greater than 3 are regarded as having the potential to bioaccumulate in the environment.
It is evident from the information obtained in the hydrolysis test and data relating to the pH of the test material in water that negligible hydrolysis of the sample solutions occurred during the course of the partition coefficient test.
The n-octanol saturated water was adjusted to pH 7. Testing at neutral pH by the flask method is the preferred choice for test materials that are salts.
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient of the test material has been determined to be 6.96 x l0-4 at 21.6°C +/- 0.5°C. The log10 Pow = - 3.16.
- Executive summary:
Introduction:
The study has been conducted according to 92/69/EEC, EC method A8 (shake-flask method)
Results and Conclusions
The partition coefficient of the test material has been determined to be 6.96 x l0-4 at 21.6°C +/- 0.5°C. The log10 Pow = - 3.16.
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