Registration Dossier
Registration Dossier
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EC number: 229-633-2 | CAS number: 6635-20-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- publication
- Title:
- Problem of the toxicity of vanillin
- Author:
- Makaruk MI
- Year:
- 1 980
- Bibliographic source:
- Gig Sanit, 6, 78-80
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- GLP compliance:
- not specified
- Test type:
- other: no data
Test material
- Reference substance name:
- Vanillin
- EC Number:
- 204-465-2
- EC Name:
- Vanillin
- Cas Number:
- 121-33-5
- Molecular formula:
- C8H8O3
- IUPAC Name:
- 1-butoxypropan-2-ol
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: vapour
- Vehicle:
- not specified
- Details on inhalation exposure:
- * Chamber description:
- Exposure chamber volume: 100 L - Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 4 h
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- > 41.7 mg/m³ air
- Based on:
- test mat.
- Exp. duration:
- 4 h
- Mortality:
- no mortality observed
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LC50 valuie of Vanillin is above 41 mg/m3 which is the value of saturated vapour concentration
- Executive summary:
The LC50 valuie of Vanillin is above 41 mg/m3 which is the value of saturated vapour concentration
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