Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information


The hydrolysis of Incorez 397 in different aqueous buffer solutions (pH = 4, 7 and 9) at room temperature (25 °C) was investigated using LC/MS and MS/MS. After 5 minutes hydrolysis under these conditions Incorez 397 could not be detected (t1/2 < 5 minutes). It could be shown that the hydrolysis of Incorez 397 was independent from the pH of the aqueous media. The degradation products (1,3-cyclohexanebis (methylamine) and isobutyraldehyde) were successfully identified using reference spectra. Recovery data showed that 1,3-cyclohexanebis(methylamine) was quantitatively formed from Incorez 397 in different aqueous buffer solutions (pH = 4, 7, 9).The storage stability of 1,3-Cyclohexanebis(methylamine) in different buffer solutions (pH = 4, 7 and 9) at room temperature was determined to be at least 5 days.



Incorez 397 was assessed in a closed bottle test in accordance to OECD guideline 301 D and EU method C.4 VI. The test item was exposed to activated sludge from an aeration tank for 28 days. Under the test conditions the percentage biodegradation of Incorez 397 reached a mean of 5.9 % based on ThODNO3. Thus, Incorez 397 was not ready biodegradable.


Transport and distribution:

The test method for the determination of the adsorption coefficient (Koc) of a substance as described for liquid materials in test guideline C.19 of EC Regulation 440/2008 was replaced by a theory based evaluation. Due to the fast and spontaneous hydrolysis of Incorez 397 upon contact with water, experimental determination of the Koc was technically not feasible. The log Koc of Incorez 397 was calculated using the US EPA EPIWIN (v4.0) software. The resulting log Koc was 5.13.