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Toxicity to aquatic algae and cyanobacteria

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Description of key information

Long-term toxicity to aquatic algae:
Conclusion: Results from two studies show that DTDP does not produce toxicity to algae at or below its maximum attainable water solubility.

Key value for chemical safety assessment

Additional information

Both substances named DTDP are high molecular weight phthalate esters (C13), diisotridecyl phthalate (CAS number 27253-26-5, EC number 248-368-3) and 1,2-Benzenedicarboxylic acid, di-C11-14-branched alkyl esters, C13-rich (CAS number 68515-47-9, EC number 271-089-3). Both are isomeric mixtures of C13 branched alkyl esters, the starting material being different but both starting materials consisting of various isomers of multibranched C13 alcohols.

The results of algal toxicity studies are reported EC50 and NOEC values. The NOEC values represent the highest concentration measured in these studies that did not demonstrate effects. In all cases this was the highest concentration attainable and measured under the conditions of the study. The use of the NOEC values in the results overview table to derive values for quantitative risk assessment is inappropriate as they are not true NOEC values.

I5 Summary

The data used to characterize the algal toxicity of di-isotridecyl phthalate ester (DTDP) are consistent with the data for several high molecular weight phthalate diesters summarized by Staples et al. (1997). These data show that high molecular weight phthalate diesters do not produce toxicity to algae at or below their maximum attainable solubility. The algal dataset includes results for two species, Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata) and Scenedesmus subspicatus (new name: Desmodesmus subspicatus).

Staples et al. (1997). Aquatic toxicity of eighteen phthalate esters. Environ. Toxicol. Chem. 16(5): 875 -891.

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