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Short-term toxicity to fish

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Short-term toxicity to fish:
Conclusion: Results from short-term toxicity studies with several species of fish show that DTDP does not cause toxicity at the maximum achievable aqueous concentrations investigated in these tests (i.e. in excess of water solubility).

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Additional information

Both substances named DTDP are high molecular weight phthalate esters (C13), diisotridecyl phthalate (CAS number 27253-26-5, EC number 248-368-3) and 1,2-Benzenedicarboxylic acid, di-C11-14-branched alkyl esters, C13-rich (CAS number 68515-47-9, EC number 271-089-3). Both are isomeric mixtures of C13 branched alkyl esters, the starting material being different but both starting materials consisting of various isomers of multibranched C13 alcohols.

The results of acute fish toxicity studies are reported as LC50and NOEC values. The NOEC values represent the highest concentration measured in these studies that did not demonstrate mortality. In all cases this was the highest concentration attainable and measured under the conditions of the study. The use of the NOEC values reported in the results overview table to derive values for quantitative risk assessment is inappropriate as they are not true NOEC values.

I5 Summary:

The data used to characterize the fish acute toxicity of DTDP are consistent with the data for several high molecular weight phthalate diesters summarized by Staples et al. (1997). These data show that high molecular weight phthalate diesters do not produce acute toxicity to fish at or below their maximum attainable water solubliity. The acute fish dataset includes results for various species of freshwater fish including Oncorhynchus mykiss, Pimephales promelas, and Lepomis macrochirus, and a marine fish, Cyprinodon variegatus.

Staples et al. (1997). Aquatic toxicity of eighteen phthalate esters. Environ. Toxicol. Chem. 16(5): 875 -891.

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