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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Description of key information

The dissociation constants for 1,5-bis[1,2-bis(ethoxycarbonyl)ethylamino]-2-methylpentane are estimated to be pKa1 of 6.6 and pKa2 of 6.7, at 25°C.
Calculated with the software ACD/ChemSketch (ACD/Percepta version 14.00).

Key value for chemical safety assessment

pKa at 20°C:

Additional information

In the scope of a study to determine the n-octanol/water- partition coefficient of the test item, it was shown that pKa values could not be determined experimentally due to solubility problems. For this reason, the QSAR-Estimation for the dissociation constant was chosen as key-study and no experiments were conducted.

According to the estimated results, this substance presents mainly as ionic form under environmentally relevant pH5 - 9.