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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-12-14 to 2011-12-29
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
signed 2010-08-25
Type of method:
effusion method: vapour pressure balance
Key result
Temp.:
20 °C
Vapour pressure:
0.74 Pa
Remarks on result:
other: Calculated vapour pressure
Temp.:
25 °C
Vapour pressure:
1.4 Pa
Remarks on result:
other: Calculated vapour pressure
Temp.:
50 °C
Vapour pressure:
29 Pa
Remarks on result:
other: Calculated vapour pressure

Results of the Effusion method




















































No.



Temperature / °C



Vapour pressure / Pa



1



18



5.59 ×10-1



2



19.5



7.08 ×10-1



3



21.5



9.47 ×10-1



4



23.5



1.23 ×10-0



5



25.5



1.27 ×10-0



6



27.5



2.14 ×10-0



7



29



2.51 ×10-0



8



34.5



4.80 ×10-0




 


 


 


 


 


 


The vapour pressure values >25 °C are already slightly above the upper limit of the vapour pressure balance, but due to the limited abbreviation from the upper limit and the very good fit to the regression, these values can also be used for the evaluation of the data.


From the measured data points of the vapour pressure curve the constants A and B of the Antoine equation


log10p = A + (B/T)


can be derived by regression of the data points to


A = 17.0676


B = -5041.19.


The vapour pressure of the test itemSymSitive®1609 purcalculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation EC 440/2008 Method A.4.Vapour Pressureare shown in the following table:


 Calculated vapour pressure values for 20, 25 and 50 °C























Temperature / °C



Vapour pressure / Pa



20



7.4 ×10-1



25



1.4 ×10-0



50



2.9 ×10+1



Conclusions:
According to Regulation EC 440/2008 Method A.4 and OECD 104 the vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20 °C: 0.74 Pa; 25 °C: 1.4 Pa and 50 °C: 29 Pa.

Description of key information

key data vapour pressure: 20 °C: 0.74 Pa; 25 °C: 1.4 Pa; 50 °C: 29 Pa.

Key value for chemical safety assessment

Vapour pressure:
0.74 Pa
at the temperature of:
20 °C

Additional information

According to Regulation EC 440/2008 Method A.4 and OECD 104 the vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20 °C: 0.74 Pa; 25 °C: 1.4 Pa and 50 °C: 29 Pa.