Registration Dossier
Registration Dossier
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EC number: 940-123-5 | CAS number: 866889-74-9
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The following results from supporting substances are used for justification of read-across:
The solubility of Stearic acid 3-(dimethylaminopropyl)amide in n-Octanol was determined according to OECD guideline 105, 27 July 1995, adapted for n-Octanol (flask method). The solubility of Stearic acid 3-(dimethylaminopropyl)amide in n-Octanol is 151 g/L.
A supporting study is available, in which the solubility of Stearic acid 3-(dimethylaminopropyl)amide in n-Octanol was determined by HPLC/CAD.
The average solubility of Stearic acid 3-(dimethylaminopropyl)amide in n-Octanol was 21.6 ± 0.98%. The density of the saturated mixture was determined to be 0.832 ± 0.003 g/mL. Using the density, the solubility of Stearic acid 3-(dimethylaminopropyl)amide in n-Octanol can be converted into 180 ± 8 g/L.
The solubility of Stearic acid 3-(dimethylaminopropyl)amide hydrochloride in n-Octanol was determined according to OECD guideline 105, 27 July 1995, adapted for n-Octanol (flask method). The solubility of Stearic acid 3-(dimethylaminopropyl)amide hydrochloride in n-Octanol is 22 g/L.
The solubility of C22-trimethylammoniumchlorid in n-Octanol was determined following the OECD guideline 105 and Directive 92/69/EC Method A.6 (guidelines adapted to the purpose of the study). The solubility of the test item C22-trimethylammoniumchlorid in n-Octanol was determined using the flask method. The test mixtures were incubated at 30 +- 0.5°C for 72, 48 and 24 hours and the solubility was measured after 24 h at 20 +- 0.5°C. The solubility of C22-trimethylammoniumchlorid in n-Octanol was 19.7 g/L at 20°C.
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