Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 940-123-5 | CAS number: 866889-74-9
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
28 d NOEC (mortality, reproduction, Folsomia candida) = 500 mg/kg soil DW; ISO 11267, RL1, GLP; read-across from C20/22 ATQ
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for soil dwelling arthropods:
- 500 mg/kg soil dw
Additional information
No experimental data are available for C16-18 DMAPA amidoamine. However, studies are available with the source substance C20/22ATQ. For justification for read-across see endpoint summary "Terrestrial toxicity".
The effects of C20/22 ATQ on the reproduction of Folsomia candida in artificial soil were examined in a laboratory study. The study was carried out based on ISO 11267 (1999) and OECD Draft (2008).
The aim of the test was to determine the effects of the test item on the reproduction of Folsomia candida in artificial soil by cutaneous and alimentary uptake.The test item was incorporated once into artificial soil with the test item concentrations 62.5 – 125 - 250 – 500 – 1000 mg/kg DW. The control was artificial soil without the test or reference item. Additionally a solvent control was tested. Folsomia candida (12 days old) were placed into artificial soil. For the control and solvent control 8 replicates and for the test item 5 replicates were tested. In each replicate 10 juveniles were inserted. During exposure springtails were fed with granulated dry yeast. After 28 days, mortality and reproduction were assessed.
Test item |
C20/22 ATQ |
|
Test object |
Folsomia candida |
|
Exposure |
Artificial soil |
|
Adult mortality |
Reproduction |
|
LOEC [mg/kg DW] |
1000 |
1000 |
NOEC [mg/kg DW] |
500 |
500 |
LD50/ EC50 [mg/kg DW] |
> 1000 |
> 1000 |
The validity of the study was evaluated according to ISO 11267 (1999) and OECD Draft (2008). Control mortality should be 20%. In this study the mean control mortality (pooled controls) was 13.8%. The reproduction rate should be >/= 100 instars per control replicate. In this study the reproduction rate was between 245 and 670 instars per control replicate (pooled control).The coefficient of variation of the reproduction rate in the control should be 30.0%. In this study the coefficient of variation in the pooled controls was 25%.Thus, this study was considered to be valid.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
