1,4-Benzodioxane-2-carboxylic acid

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 2018-12-24 to 2019-03-22

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study performed to current OECD guidelines with no significant deviations and run in OECD GLP certified lab.

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

Purity: 99.7%
Batch No.: 80031745a

Key result

Decomposition:

yes

Decomp. temp.:

> 250 °C

Remarks on result:

other: the test item has no boiling temperature

Preliminary Test

Starting at 250°C, the weight of the sample decreased significantly. At 320°C, the sample weight had decreased by 25%.

After the experiment, a black molten residue remained in the sample container (original colour:off-whitebased on visual observation of a technician). The change of the colour indicated reaction and/or decomposition of the test item.

Main Study

An endothermic effect was observed between 100°C and 150°C followed by an endothermic effect starting at 250°C. The extrapolated onset temperature of the first effect was 124.513°C. The endothermic effect was most likely obtained due to melting of the test item. The second endothermic effect was probably obtained due to reaction and/or decomposition of the test item.

After the experiment, a dark brown molten residue remained in the sample container (original colour: off white based on visual observation of a technician). The change of the colour indicated reaction and/or decomposition of the test item. Based on this visual observation, it was found that the test item had molten and the change of the colour demonstrated reaction and/or decomposition of the test item.

In order to investigate the endothermic effect, Experiment 2 was stopped directly after the melting effect. The extrapolated onset temperature was 124.609°C. After the experiment, a white molten residue remained in the sample container (original colour: off white based on visual observation of a technician). It demonstrated that melting was the reason for the endothermic effect.

The melting temperature was determined as the mean melting temperature of Experiment 1 (124.513°C) and Experiment 2 (124.609°C).

Conclusions:

Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 250°C (> 523K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Executive summary:

The boiling temperature of the test item were determined by DSC.

Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 250°C (> 523K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Description of key information

Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 250°C (> 523K).  Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started.  Based on this, the test item has no boiling temperature.

Additional information

The boiling temperature of the test item were determined by DSC.

Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 250°C (> 523K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.