Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

LD50 values of 80 -150 mg/kg bw were obtained from acute oral toxicity studies performed in rats. Classification as acute toxicity category 3 is applicable according to the CLP criteria along with hazard statement H301 : toxic if swallowed. The determination of acute inhalation and acute dermal toxicity was performed by calculation using the available acute oral toxicity and kinetic data. Classification as acute toxicity category 4 is applicable according to the CLP criteria along with hazard statement H332 : harmful if inhaled. The substance is not classified regarding acute dermal toxicity according to the CLP criteria.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
80 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LC50
Value:
1 130 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
14 032 mg/kg bw

Additional information

Justification for classification or non-classification

LD50 values of 80 -150 mg/kg bw were obtained from acute oral toxicity studies performed in rats. Classification as acute toxicity category 3 is applicable according to the CLP criteria along with hazard statement H301 : toxic if swallowed. The determination of acute inhalation and acute dermal toxicity was performed by calculation using the available acute oral toxicity and kinetic data. Classification as acute toxicity category 4 is applicable according to the CLP criteria along with hazard statement H332 : harmful if inhaled. The substance is not classified regarding acute dermal toxicity according to the CLP criteria.