Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The LC50 to Danio rerio after 96 hours was determined to be >77.9mg/L. The NOEC (0 -96 hours) was determined to be 77.9mg/L.

Based on measured concentrations of the test item hydroxyethyl-p-phenylenediamine sulfate, the 48 hour EC50 for Daphnia magna was determined to be 3.48 mg/L.

Hydroxyethyl-p-phenylenediamine sulfate was found to inhibit the growth of the freshwater green alga Desmodesmus subspicatus at nominal concentrations >= 6.25mg/L (biomass growth) and >=25mg/L (growth rate) corresponding to mean measured concentrations of >=2.98 and >=11.7mg/L respectively. The EC50 values for inhibition of biomass growth (EbC50) and specific growth rate (ErC50) after 72 hours were nominal 19 mg/L and 41 mg/L respectively and mean measured 8.7 mg/L and 19.0 mg/L respectively. Inhibition effects were found to be reversible up to the nominal concentration of 100mg/L (all effect levels given as nominal and mean measured concentrations).

The EC50 value of the test item hydroxy-p-phenylenediamine sulfate for toxicity to microorganisms was determined to be 185mg/L.

Additional information