Registration Dossier
Registration Dossier
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EC number: 265-332-2 | CAS number: 65059-42-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019.03.12~2019.05.20
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Trimethyloctylammonium methyl sulphate
- EC Number:
- 265-332-2
- EC Name:
- Trimethyloctylammonium methyl sulphate
- Cas Number:
- 65059-42-9
- Molecular formula:
- C11H26N.CH3O4S
- IUPAC Name:
- trimethyl(octyl)azanium methyl sulfate
Constituent 1
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
Test conditions
- Test temperature:
- (21 - 24)℃
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- >= 12.83 - <= 14.97 mg/L
- Nominal / measured:
- nominal
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 1.12 mg/L
- Nominal / measured:
- nominal
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- ca. 3.54 mg/L
- Nominal / measured:
- nominal
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 72 h-EC50 of Trimethyloctylammonium methyl sulphate for freshwater alga ,Pseudokirchneriella subcapitata, is as follows. EC50, NOEC, and LOEC is expressed in measured concentration.
Inhibition rate on the average specific growth rate,
- 72 h-ErC50 : 13.86 mg/L {95 % confidence interval : (12.83 - 14.97) mg/L}
- 72 h-NOEC : 1.12 mg/L
- 72 h-LOEC : 3.54 mg/L (Annex 6, 7).
Inhibition rate on the yield,
- 72 h-ErC50 : 4.22 mg/L {95% confidence interval : (4.00 - 4.44) mg/L}
- 72 h-NOEC : 0.42 mg/L
- 72 h-LOEC : 1.12 mg/L (Annex 8, 9).
No factors influencing the test occurred during the study.
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