Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-332-2 | CAS number: 65059-42-9
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019.03.07~2019.05.20
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- 13 April 2004
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Trimethyloctylammonium methyl sulphate
- EC Number:
- 265-332-2
- EC Name:
- Trimethyloctylammonium methyl sulphate
- Cas Number:
- 65059-42-9
- Molecular formula:
- C11H26N.CH3O4S
- IUPAC Name:
- trimethyl(octyl)azanium methyl sulfate
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia magna
Test conditions
- Hardness:
- (140 - 250) mg/L
- Test temperature:
- 19 - 21) ℃, change of water temperature within ± 1 ℃
- pH:
- 6.0 - 9.0
- Dissolved oxygen:
- ≧ 3 mg/L (control and treated group)
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 15.94 mg/L
- Nominal / measured:
- nominal
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 10.78 mg/L
- Nominal / measured:
- nominal
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 9.176 mg/L
- Nominal / measured:
- nominal
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 5.329 mg/L
- Nominal / measured:
- nominal
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The study was conducted to assess the acute toxicity of Trimethyloctylammonium methyl sulphate to Daphnia magna under static system. Determination of EC50 and NOEC was based on measured concentration (Table 6).
- 24 h-EC50 : 15.94 mg/L, [95 % confidence limit (14.53 - 17.48) mg/L]
- 48 h-EC50 : 10.78 mg/L, [95 % confidence limit (9.301 - 12.37) mg/L]
- 24 h-NOEC : 9.176 mg/L
- 48 h-NOEC : 5.329 mg/L
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
