Registration Dossier
Registration Dossier
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EC number: 230-565-0 | CAS number: 7195-44-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
The maximization test perfomed with bis(2,3 -epoxypropyl)terephthalate showed a significant potential to cause skin sensitisation.
Migrated from Short description of key information:
A Magnusson & Kligman test was performed in Guinea Pig. 95% of the test animals were sensitised.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No data available
Justification for classification or non-classification
- skin sensitisation:
Based on the above stated assessment of the skin sensitisation potential of bis (2,3-epoxypropyl) terephthalate (95% of the animals sensitized in Magnuson & Kligman test) the substance needs to be classified as R43 (May cause sensitisation by skin contact)according to Council Directive 2001/59/EC (28th ATP of Directive 67/548/EEC) and accordingCLP (Regulation (EC) No 1272/2008 Of The European Parliament And Of The Council)as implementation of UN-GHS in the EU.
- respiratory sensitisation:
As no data on respiratory sensitization is available for bis(2,3 -epoxypropyl) terephthalate a classification is not possible according to Council Directive 2001/59/EC (28th ATP of Directive 67/548/EEC) and accordingCLP (Regulation (EC) No 1272/2008 Of The European Parliament And Of The Council)as implementation of UN-GHS in the EU.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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