Registration Dossier
Registration Dossier
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EC number: 470-680-5 | CAS number: 958872-63-4
Endpoint summary
Administrative data
Description of key information
Skin irritation: OECD guideline 404 and EU method B.4. GLP.
Eye irritation: OECD guideline 405 and EU method B.5. GLP.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Skin irritation: No corrosion or irritation were apparent (all scores 0) following a 4 hours period of exposure to the test item.
Eye irritation:
The results indicate that based upon classification criteria of European Directives concerning the classification, packaging and labelling of dangerous substances (67/548/EEC and subsequent revisions) Dipropylen glycol isobornyl ether (mixture of isomers) is not irritating to eyes.
According to the CLP Regulation, the substance is classified as Eye irritant, Category 2, based on the scores obtained for the corneal opacity (calculated as the mean scores following grading at 24, 48 and 72 h) which are above 1 for the three animals and which fully reverses within the observation period.
Effects on eye irritation: irritating
Justification for classification or non-classification
According to the CLP Regulation, the substance is classified as Eye irritant, Category 2, based on the scores obtained for the corneal opacity (calculated as the mean scores following grading at 24, 48 and 72 h) which are above 1 for the three animals and which fully reverses within the observation period.
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