Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

28-day study: OECD guideline 407. GLP. 

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Dose descriptor:
NOAEL
1 000 mg/kg bw/day
Study duration:
subacute
Species:
rat

Additional information

A daily oral administration of the test item to Wistar rats at a dose level of 200, 500 and 1000 mg/kg body mass over a time period of 28 days resulted in only mild systemic and local effects in test animals treated with the high dose (1000 mg /kg).

Justification for classification or non-classification

Based on the available data, the substance is not classified.