Registration Dossier
Registration Dossier
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EC number: 240-464-3 | CAS number: 16415-12-6
Endpoint summary
Administrative data
Description of key information
Additional information
Upon contact with water, the submission substance hexadecyl(trimethoxy)silane (CAS No. 16415-12-6) hydrolyses slowly under environmentally relevant conditions to form the hydrolysis products hexadecylsilantriol and methanol (DT50 > 14 d at pH 4 - 10). Therefore, the environmental hazard assessment for the aquatic compartment is based on the properties of the parent substance, in accordance with REACH guidance for Chemical Safety Assessment R.16 (ECHA, 2016).
For the short-term toxicity to aquatic organisms, experimental studies are available for all three trophic levels. All studies were performed according to standard testing guidelines and in compliance with GLP. The test concentrations applied were well above the limit of water solubility. No short-term toxic effects were observed towards the tested organisms of all three trophic levels up to the highest tested concentration. Due to the very low water solubility of the substance, the long-term toxicity to aquatic invertebrates was also investigated. This chronic study did not indicate any long-term toxicity toward Daphnia magna, resulting in a NOEC of ≥ 10 mg/L.
Furthermore, no toxic effects toward activated sludge microorganisms were observed in the available experimental study which resulted in an EC10 (3 h) of > 100 mg/L.
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