Reaction mass of 3-(difluoromethyl)-1-methyl-N-[(1RS,4SR,9RS)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide and of 3-(difluoromethyl)-1-methyl-N-[(1RS,4SR,9SR)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide; isopyrazam

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

30 May 2012 to 01 Jun 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

2008

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Atm. press.:

>= 100.9 - <= 101.8 kPa

Decomposition:

yes

Decomp. temp.:

ca. 258 °C

Remarks on result:

not determinable

Remarks:

The test substance decomposed before boiling.

Due to the initial low rate of enthalpy change during decomposition, the onset temperature could only be approximated. From the six determinations, a mean onset temperature of 273 °C (546 K) was obtained from the pre-exotherm baseline limits, with a relative standard deviation value of 4.7 %. The extrapolated onset temperature of the first exotherm was much more repeatable, with a mean extrapolated onset temperature of 305 °C (579 K) and a relative standard deviation value of 0.8 %. However, the overall conclusion has been taken as the lowest onset temperature at which decomposition was detected, in order to present a worst case scenario for thermal stability.

The similarity between thermograms obtained in air and nitrogen atmospheres supported that the observed decomposition was thermal and not oxidative. The test item decomposed on heating from approximately 258 °C (532 K), both in air and under a nitrogen atmosphere. Therefore, the boiling temperature cannot be determined.

Conclusions:

The test substance decomposed on heating from approximately 258 °C (532 K), both in air and under a nitrogen atmosphere. Therefore, the boiling temperature cannot be determined.

Executive summary:

The boiling point of the test substance was determined according to OECD TG 103 following GLP principles. The determinations were carried out by differential scanning calorimetry (DSC) using the procedure specified in ASTM E537-86. The thermal behaviour of the test substance was investigated, not only in air, but also under a nitrogen atmosphere using a heating rate of 20.0 °C / minute and starting from 20.0 °C.

Due to the initial low rate of enthalpy change during decomposition, the onset temperature could only be approximated. From the six determinations, a mean onset temperature of 273 °C (546 K) was obtained from the pre-exotherm baseline limits, with a relative standard deviation value of 4.7 %. The extrapolated onset temperature of the first exotherm was much more repeatable, with a mean extrapolated onset temperature of 305 °C (579 K) and a relative standard deviation value of 0.8 %. However, the overall conclusion has been taken as the lowest onset temperature at which decomposition was detected, in order to present a worst case scenario for thermal stability.

The similarity between thermograms obtained in air and nitrogen atmospheres supported that the observed decomposition was thermal and not oxidative.

The test c decomposed on heating from approximately 258 °C (532 K), both in air and under a nitrogen atmosphere. Therefore, the boiling temperature cannot be determined.

Description of key information

The test substance decomposed on heating from approximately 258 °C (532 K), both in air and under a nitrogen atmosphere. Therefore, the boiling temperature cannot be determined.

Key value for chemical safety assessment

Temperature of decomposition (state purity):

258 °C