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EC number: 217-130-0 | CAS number: 1747-60-0
Endpoint summary
Administrative data
Description of key information
Data generated for short term exposure to fish on 2-Amino-6-methoxybenzothiazole by means of VEGA QSAR prediction model generally suggest threshold of toxicity in the range of about 1 to 19.26 mg/L, whereas data generated for aquatic invertebrates suggest a range of toxicity between 1.31 to 1.65 mg/L.
Additional information
Prediction analysis performed using the VEGA QSAR Model:
- Prediction is between 1 and 10 mg/L, but the result may be not reliable. Reliability: the predicted compound is outside the Applicability Domain of the model. [Fish Acute (LC50) Toxicity classification (SarPy/IRFMN) 1.0.3]
- Prediction is 11.49 mg/L, but the result may be not reliable. Reliability: the predicted compound is outside the Applicability Domain of the model. [Fish Acute (LC50) Toxicity model (NIC) 1.0.1]
- Prediction is 19.26 mg/L, but the result may be not reliable. Reliability: the predicted compound is outside the Applicability Domain of the model. [Fathead Minnow LC50 96h (EPA) 1.0.8]
Prediction analysis performed using the VEGA QSAR Model:
- Prediction is 1.65 mg/L, but the result may be not reliable. Reliability: the predicted compound is outside the Applicability Domain of the model. [Daphnia Magna LC50 48h (EPA) 1.0.8]
- Prediction is 1.31 mg/L, but the result may be not reliable. Reliability: the predicted compound is outside the Applicability Domain of the model. [Daphnia Magna LC50 48h (DEMETRA) 1.0.4]
For all the predictions the compound is outside the Applicability Domain of the model, thus data derived for aquatic classification should be critically evaluated. For this reason, as no other conventional studies have been performed both on 2-Amino-6-methoxybenzothiazole as well as on structurally similar compounds and considering that derived results are outside the Applicability Domain of the model no classification for aquatic toxicity is warranted for 2-Amino-6-methoxybenzothiazole.
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