Registration Dossier
Registration Dossier
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EC number: 500-046-6 | CAS number: 26183-52-8 1 - 2.5 moles ethoxylated
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22.07.2019 - 29.07.2019
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM E 1148-02 (falsk method)
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 82 µg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 1.5 g/L
- Incubation duration:
- 72 h
- Temp.:
- 25 °C
- pH:
- ca. 6.5
- Water solubility:
- 76 µg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 500 mg/L
- Incubation duration:
- 72 h
- Temp.:
- 25 °C
- pH:
- ca. 6.5
Reference
|
Sample 1 |
Sample 2 |
Sample 3 |
Sample 4 |
Sample 5 |
Sample 6 |
Weight |
739.1 mg |
792.6 |
809.5 |
2227.0 |
2263.7 |
2212.7 |
Volume of water |
1500 mL |
1500 mL |
1500 mL |
1500 mL |
1500 mL |
1500 mL |
Temperature of dissolution |
25 ± 1 °C |
25 ± 1 °C |
25 ± 1 °C |
25 ± 1 °C |
25 ± 1 °C |
25 ± 1 °C |
Starting date of dissolution |
2019-07-22 |
2019-07-24 |
2019-07-26 |
2019-07-22 |
2019-07-24 |
2019-07-26 |
Starting time of dissolution |
08:00 |
8:00 |
08:00 |
08:00 |
08:00 |
08:00 |
Final date of dissolution |
2019-07-23 |
2019-07-26 |
2019-07-29 |
2019-07-23 |
2019-07-26 |
2019-07-29 |
Final time of dissolution |
08:00 |
08:00 |
08:00 |
08:00 |
08:00 |
08:00 |
|
|
|
|
|
|
|
Dissolution time |
24 h |
48 h |
72 h |
24 h |
48 h |
72 h |
Centrifugation time |
0 min |
0 |
30 |
30 |
30 |
30 |
Filtration |
no |
no |
no |
no |
yes |
yes |
pH value |
6 - 7 |
6 - 7 |
6 - 7 |
6 - 7 |
6 - 7 |
6 - 7 |
|
|
|
|
|
|
|
Concentration of HPLC standard solution [µg/mL] |
72 |
72 |
72 |
72 |
72 |
72 |
|
|
|
|
|
|
|
Peak area 1 standard |
7517 |
7517 |
7517 |
7517 |
7517 |
7517 |
Peak area 2 standard |
7598 |
7598 |
7598 |
7598 |
7598 |
7598 |
Average peak area standard |
7558 |
7558 |
7558 |
7558 |
7558 |
7558 |
|
|
|
|
|
|
|
Peak area sample 1 |
7681 |
7709 |
7986 |
7714 |
8159 |
8604 |
Peak area sample 2 |
7724 |
7673 |
7901 |
7845 |
8160 |
8515 |
Average peak area sample |
7703 |
7691 |
7944 |
7780 |
8160 |
8560 |
|
|
|
|
|
|
|
Measured dissolved concentration [µg/mL] |
73.2
|
73.4 |
76.1
|
73.5
|
77.7 |
82.0 |
Description of key information
82 µg/L at 25 °C, pH = 6-7
Key value for chemical safety assessment
- Water solubility:
- 82 µg/L
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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