Registration Dossier
Registration Dossier
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EC number: 252-743-7 | CAS number: 35835-94-0
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October 2017 until April 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- not specified
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- >= 92.4 - <= 95.2 other: %w/w
- Conc. based on:
- test mat. (total fraction)
- Temp.:
- 20 °C
- pH:
- 6.3 - 7.6
- Details on results:
- During preliminary investigations, the concentration of test item in the aqueous solutions was determined to be close to the loading rates used. Therefore, it was decided to start preliminary testing at approximately 50:50 w/w and increase the loading rate.
The standard EC A.6 / OECD 105 methodology was not applicable to this test item due to its high solubility in water.
Overall, a range of sample concentrations ranging from 50 to 95% w/w of solution were prepared for visual assessment. - Conclusions:
- The water solubility of the test item has been determined to be in the range 92.4 to 95.2 % w/w of solution at 20.0 ± 0.5 °C.
- Executive summary:
Water Solubility. In the range 92.4 to 95.2 % w/w of solution at 20.0 ± 0.5 °C, by visual assessment using a modified flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Reference
Description of key information
The water solubility of the test item has been determined to be in the range 92.4 to 95.2 % w/w of solution at 20.0 ± 0.5 °C. The average of 938 g/L was used in the endpoint summary.
Key value for chemical safety assessment
- Water solubility:
- 938 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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