Registration Dossier
Registration Dossier
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EC number: 302-766-4 | CAS number: 94134-01-7
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
N,N'-bis(carboxymethylglycine) compound with 2 -aminoethanol (1:3) is not deemed to be persistent in the marine environment based on the results of an OECD 301D and an OECD 306a ready biodegradability tests, during which ready biodegradability >100% and 88% at day 28. It is then concluded that the substance is not regarded as fulfilling the criteria for Persistence (P or vP).
The partition coefficient (log Kow) of the registered substance was determined to be below 0 indicating a lack of potential to bioaccumulate. Therefore, the substance does not meet the B or vB criteria.
In accordance with Annexes VII and VIII of REACH, no long-term toxicity study on the registered substance were performed for the purpose of this registration and no data on the long-term toxicity for marine/freshwater organisms was identified. Data on short-term toxicity of the registered substance to fish, aquatic invertebrates, and algae was provided. All L(E)C50 for short-term toxicity were above 1 mg/L and therefore above screening values for T properties described in Table R.11-6 of the Guidance on Information Requirements and Chemical Safety Assessment Chapter R.11: PBT/vPvB assessment (ECHA, 2017).
The toxicity of the substance was investigated in accordance with Annexes VII and VIII of REACH. In accordance with Regulation EC No 1272/2008, it was concluded that N,N’-bis(carboxymethylglycine) compound with 2-aminoethanol (1:3) does not meet the criteria for classification as carcinogenic category 1A or 1B, germ cell mutagenic category 1A or 1B, toxic for reproduction category 1A, 1B or 2, or STOT RE category 1 or 2. Therefore, the substance does not meet the T criteria.
N,N'-bis(carboxymethylglycine) compound with 2 -aminoethanol (1:3) does not meet the PBT and the vPvB criteria. It is not considered relevant to further investigate the PBT or vPvB properties of the substance.
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