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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015-05-11
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
other: ISO 13320-1
Principles of method if other than guideline:
Laser diffraction method - The test was conducted according to the guidance of the apparatus used. A short description is given below:
The dry test substance is dispersed and passes a laser in form of an aerosol. In dependence on the particle size the laser is diffracted. The resulting so called “Fraunhofer” diffraction spectrum is bundled using a converging lens in a multi-element photo detector. In dependence of the particle size distribution a radial symmetric intensity distribution is generated. The measured intensity is analysed by a computer and converted into a particle size distribution.
GLP compliance:
not specified
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Key result
Percentile:
D10
Mean:
7.87 µm
Remarks on result:
other: St. dev. not available
Key result
Percentile:
D50
Mean:
25.42 µm
Remarks on result:
other: St. dev. not available
Key result
Percentile:
D90
Mean:
107.19 µm
Remarks on result:
other: St. dev. not available
Key result
Percentile:
D95
Mean:
255.53 µm
Remarks on result:
other: St. dev. not available

SMD = 16.85 µm (Sauter Mean Diameter)

VMD = 50.34 µm (Volume Mean Diameter)

Conclusions:
Particle size distribution of Caprinoguanamin was determined by Laser scattering/diffraction

D10 7.87 µm
D50 25.42 µm
D90 107.19 µm

Description of key information

Particle size distribution of Caprinoguanamin was determined by Laser scattering/diffraction

D10 7.87 µm

D50 25.42 µm

D90 107.19 µm

Additional information