Registration Dossier
Registration Dossier
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EC number: 241-300-3 | CAS number: 17265-14-4
Endpoint summary
Administrative data
Description of key information
Additional information
No data on aquatic toxicity of the salt disodium sebacate are available. Only following data on the acid are available:
Fish:
No acute toxic effects on fresh or marine water fish were observed (Ausimont, 1999; BASF SE, 2009).
Aquatic invertebrates:
No mortality was observed in the freshwater organism Daphnis magna (Ausimont, 1999). EC50 48h (acid) > 100mg/L
For the marine copepod Acartia tonsa, an LC50 of 18 mg/L was determined with the acid (BASF SE, 2009) and extrapolated for the salt to
Aquatic algae and cyanobacteria:
A growth inhibiting effect was documented and an EL50 of 38.7 mg/L was determined (BASF SE, 2009).
Microorganisms:
No respiratory inhibition was observed (BASF SE, 1990).
However, according to ECHA guidance R7b effects can be extrapolated from the anion or cation, whichever has the most toxic effect, if no data are available on a salt. If the effect is related to only one of the ions, the classification of the salt should use the effect concentration multiplied by the salt:ion molecular weight ratio.
Overview on experimental derived effect values with sebacic acid and extrapolated effect values for disodium sebacate
Endpoint |
Sebacic acid |
Disodium sebacate |
Fish (marine) LC50, 96h |
> 18 mg/L |
> 22 mg/L |
Fish (freshwater) LC50, 96h |
> 100mg/L |
> 122mg/L |
Invertebrate (marine) LC50 48h |
18 mg/L |
22mg/L |
Invertebrate (freshwater) EC50 48h |
> 100mg/L |
> 122 mg/L |
Algae (marine) EL50, NOEC 72h |
38.7 mg/L, 3mg/L |
47.2mg/L, 3.7mg/L |
Microorganisms EC20, 3h |
> 1000 mg/L |
> 1220 mg/L |
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