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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2002
Report date:
2002

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
GLP compliance:
not specified
Test type:
acute toxic class method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
6,10,14-Trimethyl-5-Pentadecen-2-on
EC Number:
609-306-4
Cas Number:
3689-69-8
Molecular formula:
C18H34O
IUPAC Name:
6,10,14-Trimethyl-5-Pentadecen-2-on
Details on test material:
Tetrahydrofarnesylaceton (THFAC), batch Nr. 01rg11.
Test substance number: 01/753-1
Purity unknown.
Specific details on test material used for the study:
purity: ca. 95%
batch no.: 01rg11

Test animals

Species:
rat
Strain:
not specified
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: olive oil
Doses:
2000 mg/kg bw
(Conc.: 40g/100 ml -> 5 ml/kg bw)
No. of animals per sex per dose:
3

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
none
Gross pathology:
organs after necropsy: no abnormalities detected

Any other information on results incl. tables

No mortality, no symptoms or treatment related organ changes were  observed.

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: EU