Registration Dossier
Registration Dossier
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EC number: 203-192-6 | CAS number: 104-29-0
Endpoint summary
Administrative data
Description of key information
Chlorphenesin is not skin sensitiser.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
An LLNA test on Chlorphenesin was performed in 2001 (study report of 2003), before the implementation of the Regulation (EC n.1223/2009) with negative results. There are few cases of sensitized people after repeated contact with cosmetic products containing Chlorphenesin as preservative. The rate is low and not enough to trigger classification as skin sensitiser.
Even though the result from epidemiological studies are questionable, as precautionary approach the classification H315 (skin irr., cat.2) is assigned according to the CLP Regulation (EC n.1272/2008).
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Chlorphenesin is not classified for skin sensitisation according to the CLP Regulation (EC.n.1272/2008). For justification see the results of available studies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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