Registration Dossier
Registration Dossier
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EC number: 203-628-5 | CAS number: 108-90-7
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
A reproductive toxicity study in two-generation rats (OECD 416) showed that Chlorobenzene, administered before mating at doses up to 450 ppm (6 hours / day, 7 days / week for 10 weeks), has no effect adverse effects on reproductive performance or fertility of rats of both sexes. The substance also did not cause any embryonic toxicity or teratogenic effect in a teratogenic study in rats and rabbits conducted in the period of major organogenesis (OECD 414) and maximum dose equal to 590 ppm.
Justification for classification or non-classification
The intermediate not met GHS criteria.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
