Registration Dossier
Registration Dossier
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EC number: 248-469-2 | CAS number: 27458-92-0
Repeated dose toxicity: other routes
Administrative data
- Endpoint:
- short-term repeated dose toxicity: other route
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Toxicity Profile Tridecanols
- Author:
- BIBRA
- Year:
- 1 988
- Bibliographic source:
- Unpublished data submitted to BIBRA by a member company
Materials and methods
- Principles of method if other than guideline:
- 9 daily iv applications of the test substance within 11 days were given to rats.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Reference substance 001
- EC Number:
- 607-896-8
- Details on test material:
- - Name of test material (as cited in study report): 50% 1-tridecanol, 50% branched chain primary isomers of tridecanol
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intravenous
- Vehicle:
- not specified
- Analytical verification of doses or concentrations:
- not specified
- Duration of treatment / exposure:
- 11 days
- Frequency of treatment:
- 9 daily applications within 11 days
Doses / concentrations
- Remarks:
- Doses / Concentrations:
720 mg/ animal (ca. 2900 mg/kg/bw)
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
No abnormalities of the blood or cellular changes in the tissues (extent of examinations not stated) were found in five rats.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
