Registration Dossier
Registration Dossier
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EC number: 257-779-7 | CAS number: 52239-04-0
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study according to internal BASF standards
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 974
- Report date:
- 1974
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Method: BASF-Test
- GLP compliance:
- no
- Test type:
- other: testing vapour saturation level
- Limit test:
- yes
Test material
- Reference substance name:
- Methyl N-ethyl-N-[4-[(5-nitro-2,1-benzisothiazol-3-yl)azo]phenyl]-β-alaninate
- EC Number:
- 257-779-7
- EC Name:
- Methyl N-ethyl-N-[4-[(5-nitro-2,1-benzisothiazol-3-yl)azo]phenyl]-β-alaninate
- Cas Number:
- 52239-04-0
- Molecular formula:
- C19H19N5O4S
- IUPAC Name:
- methyl N-ethyl-N-[4-[(5-nitro-2,1-benzisothiazol-3-yl)azo]phenyl]-β-alaninate
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- no data
Administration / exposure
- Route of administration:
- inhalation: aerosol
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: unchanged (no vehicle)
- Details on inhalation exposure:
- Inhalation by means of vapor saturated at 20°C for 8 hours. To achieve saturation, air was fed through an approx. 5 cm deep layer of the product.
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 8 h
- Concentrations:
- no data
- No. of animals per sex per dose:
- 12 rats
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 7 days
- Necropsy of survivors performed: yes - Statistics:
- NA
Results and discussion
- Preliminary study:
- NA
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC0
- Based on:
- test mat.
- Exp. duration:
- 8 h
- Remarks on result:
- not determinable due to absence of adverse toxic effects
- Remarks:
- saturation level in air
- Mortality:
- no deaths
- Clinical signs:
- other: no effects
- Body weight:
- no data
- Gross pathology:
- no effects
Any other information on results incl. tables
8 hours inhalation of a saturated atmosphere did not lead to any deaths in rats (0/12)
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 8 hours inhalation of a saturated athmosphere did not lead to any deaths in rats (0/12)
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