Registration Dossier
Registration Dossier
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EC number: 606-203-6 | CAS number: 1902-01-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study conducted in compliance with GLP regulations; analogy to structural similar substance (sodiumpanthoate)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- Principles of method if other than guideline:
- Test procedures according to EU Directive 92/69/EEC, C.4-A: Dissolved organic carbon (DOC) Die-Away method, which corresponds to the OECD guideline 301 A and international Standard ISO Standard 7827.
- GLP compliance:
- yes
Test material
- Reference substance name:
- sodium (2R)-2,4-dihydroxy-3,3-dimethyl-butanoate
- Cas Number:
- 60979-68-2
- Molecular formula:
- C6 H11 Na O4
- IUPAC Name:
- sodium (2R)-2,4-dihydroxy-3,3-dimethyl-butanoate
- Details on test material:
- Butanoic acid, 2,4-dihydroxy-3,3-dimethyl, D-, sodium salt (Natriumpantoat roh, ber 100%)
Batch No.: B 671 mixed sample
Aggregate state: liquid
Content/Composition: ca. 20 % main component
79 % water
1.5 % NaOH
388 ppm NH3
31 ppm HCN
(according to Analytical Laboratory Report No. 99L00017)
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Inoculum (6 g/L stock solution): 5 ml Inoculum concentration in the test: 30 mg/L dry weight
- Duration of test (contact time):
- 21 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Initial conc.:
- 194 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- DOC removal
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Parameter:
- % degradation (DOC removal)
- Value:
- 90 - 100
- Sampling time:
- 21 d
- Details on results:
- Kinetic of test substance (in %):
= 9 ... 13 after 3 day(s)
= 43 ... 86 after 7 day(s)
= 92 ... 97 after 14 day(s)
= 94 ... 96 after 21 Kinetic of control substance (in %):
= 90 ... 100 after 14 day(s)
Applicant's summary and conclusion
- Interpretation of results:
- readily biodegradable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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