Registration Dossier
Registration Dossier
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EC number: 810-490-5 | CAS number: 35501-23-6
Endpoint summary
Administrative data
Description of key information
Additional information
To assess the acute toxicity of N,N-Dibutylaminomethyl-triethoxysilane to aquatic invertebrates (Daphnia magna) a test according to OECD 202 was performed. In the control, solvent control (THF), and at the nominal test concentrations of 0.25, 0.50, 1.0, 2.0 and 4.0 mg/L (*1) no immobile daphnias were observed. Based on this, the test item N,N-Dibutylaminomethyl-triethoxysilane had no acute toxic effects on Daphnia magna up to the maximum technically feasible concentration of the test item or its hydrolysis products in test water under the test conditions. The EC50 value is > 4.0 mg/L, the NOEC is 4.0 mg/L.
The infuence of N,N-Dibutylaminomethyl-triethoxysilane on the growth of the freshwater green algal species Pseudokirchneriella subcapitata was assessed in a static dose-response study according OECD Guideline 201. In the control, solvent control (THF), and at the nominal test concentrations of 0.13, 0.25, 0.50, 1.0, 2.0 and 4.0 mg/L (*1) no growth or yield inhibition was observed. Thus, it can be concluded that N,N-Dibutylaminomethyl-triethoxysilane is not toxic to the green algal species Pseudokirchneriella subcapitata
up to the maximum technically feasible concentration of the test item or its hydrolysis products in test water under the test conditions. The EC50 value is > 4.0 mg/L, the NOEC is 4.0 mg/L.
(*1) Justification for using less concentrations than requested by guideline: The test concentrations and the test media preparation steps were chosen based on the results of pre-experiments to determine the solubility of the test item in the test water. The pre-experiments indicating the maximum technically feasible concentration of the test item or its hydrolysis products was already exceeded at 4.0 mg test item/L for daphnia- and algal-medium.
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