Registration Dossier
Registration Dossier
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EC number: 273-761-1 | CAS number: 69012-64-2 Amorphous silicon dioxide particles from the volatilization and vaporization of furnace feed materials in the manufacture of ferrosilicon and silicon.
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A 72-hour growth-inhibition test key study on marine alga Sceletonema costatum has been conducted for silica fume (Microsilica/Elkem ASA) at nominal concentrations of 32-10000 mg/l. (Elkem 1998). A valid supporting read-across study (soluble silica salt, pH adjusted), fresh water alga standard test Van Hoecke (2008) applied measured concentrations of dissolved silica.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 250 mg/L
- EC50 for marine water algae:
- 1 000 mg/L
- EC10 or NOEC for freshwater algae:
- 228 mg/L
- EC10 or NOEC for marine water algae:
- 323 mg/L
Additional information
A 72 -hour growth-inhibition test on marine alga Sceletonema costatum has been conducted for silica fume "Microsilica" (Elkem ASA) at nominal concentrations of 32-10000 mg/l. The highest NOEC showing no statistically significant reduction in the growth rate compared to the controls was 323 mg/l. A detailed composition of the test material or solubility of the material in artificial sea water was not reported. The test method followed the ISO 10253 (1995 E) method and GLP procedures. The nominal concentrations of EC50/NOEC 1043/323 mg/l will be used in the PNEC derivation.
A read-across study, growth-inhibition test for Pseudokirchneriella subcapitata has been conducted by applying soluble silica salt (Na2SiO3·5H2O). The toxicity of the dissolved silica was assessed in one experiment with nominal soluble silica concentrations ranging from 100 to 2,500 mg/L SiO2
The NOEC and LOEC values were 160 and 250 mg/L SiO2, respectively. The dissolved SiO2concenration was monitored analytically.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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