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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study performed using purified substance
Qualifier:
no guideline followed
Principles of method if other than guideline:
Test compound was dissolved in 25 ml methanol. 1 ml of this solution was diluted 1:10 with solutions of:0.1 N HCl (pH 1.0) Phosphate buffer (pH 6.0)Borax buffer (pH 9.0)The absorbtion spectra were measured using a spectrophotometer
GLP compliance:
yes
Dissociating properties:
no

The three spectra were identical, indicating that there is no pKa in the range pK 0 - pK10

Description of key information

no pKa in the range pK 0 - pK10 was determined.

Key value for chemical safety assessment

Additional information