Nitrotoluene

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: As cited in OECD SIDS: Guideline study without detailed documentation. Experimental details missing

Data source

Reference

Reference 1

Reference Type:

secondary source

Title:

Unnamed

Year:

2017

Report date:

2017

Reference 2

Reference Type:

publication

Title:

QSAR for biotoxiction of aromatic compounds

Author:

Liu et al

Year:

1997

Bibliographic source:

Chinese Sci Bull 42 (5): 380 - 385

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: ISO6341

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

4-nitrotoluene

EC Number:

202-808-0

EC Name:

4-nitrotoluene

Cas Number:

99-99-0

Molecular formula:

C7H7NO2

IUPAC Name:

1-methyl-4-nitrobenzene

Details on test material:

- Analytical purity: >= 98%

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

- Test organisms sieved to obtain animals less than 24 h old

Study design

Test type:

not specified

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Test conditions

Test temperature:

20 ± 2 °C

Details on test conditions:

- Each incubation vessel up to 20 Daphnids, at least 2 ml incubation medium per animal
- Daily check of oxygen concentration, pH, temperature
- No food during incubation
- Standard dilution water with Ca hardness of 250 ± 25 mg/L

Results and discussion

Effect concentrations

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

ca. 4.2 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility