Registration Dossier
Registration Dossier
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EC number: 231-598-3 | CAS number: 7647-14-5
Endpoint summary
Administrative data
Description of key information
Sodium chloride is considered to be slightly to not irritating to the skin, and moderately irritating to the eyes
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Sodium chloride is categorised under GRAS (Generally Recognised as Safe) by the FDA (U.S. Food and Drug Administration). Based on the studies available for skin and eye irritation/corrosion, sodium chloride is considered to be slightly to not irritating to the skin, and slightly irritating to the eyes.
There are no data available on the respiratory irritation potential for sodium chloride, but based on results of skin and eye irritation tested, would not be expected to be irritating.
Effects on eye irritation: moderately irritating
Effect level: empty Endpoint conclusion: Adverse effect observed
Justification for classification or non-classification
Sodium chloride is not formally classified in the EU (according to Regulation EC No. 1272/2008 Annex VI, Table 3.1 and Regulation EC No. 1272/2008 Annex VI, Table 3.2).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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