Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-598-3 | CAS number: 7647-14-5
Endpoint summary
Administrative data
Description of key information
Additional information
The acute and chronic toxicity of sodium chloride has been examined in various terrestrial species, including worms, arthropods, macrophytes, and birds. In chronic studies with terrestrial organisms, the NOEC (based on mortality) for NaCl was reported as 3507 mg/kg soil in a 10 -week study with the earthworm, Eisenia fetida. In a chronic terrestrial macrophyte study, the lowest reported NOEC of 243 mg/kg soil dw was based on stem growth in Kentucky blugrass. The mean 14 -day LC50 for sodium chloride and the earthworm, E. fetida, was 3,296 mg/kg dw. The 24-hour LD50 for silkworms was 8900 ppm NaCl when injected into the hemolymph of the larvae. In a 7-day exposure study with red fescue grass, the IC50 for germination was 500.8 mg NaCl/kg soil dw. The 12-hour LD50 for wild house sparrows was approximately 3,000 - 3,500 mg/kg NaCl. Taken together, the lowest terrestrial toxicity value was the NOEC of 243 mg/kg soil dw based on Kentucky bluegrass growth, and this value was used to calculate a PNECsoil.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
