Registration Dossier
Registration Dossier
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EC number: 201-167-4 | CAS number: 79-01-6
Endpoint summary
Administrative data
Description of key information
Additional information
For trichloroethylene short term L(E)C50s from validated sources are reported for fish, invertebrates and algae. For fish the lowest 96-h LC50 from validated data is 16 mg/l found in marine species Limanda limanda (Pearson, 1975) and and 96-h LC of 28.3 mg/l in freshwater fish (Jordanella floridae) (Smith et al., 1985). The 48h IC50 for Daphnia magna is 20.8 mg/l (Hermens, 1984) which is the lowest acute toxicity value for freshwater invertebrates, for marine invertebrates the lowest 96-h LC50 is 14 mg/l in Americamysis bahia (Ward et al., 1986). For freshwater algae the lowest toxicity value was the 72h EC50 36.5 mg/l and an EC10 of 12.3 mg/l found in Chlamydomonas reinhardtii (Brack, 1994).
In addition to short-term toxicity data, longer term toxicity data are reported for fish. A 10-day NOEC of 5.76 mg/l and a 28-day MATC of 14.85 mg/l are reported for the larvae and fry of Jordanella floridae (Smith et al., 1991). Although the study did not follow recognised testing protocols for chronic tests as described in the Technical Guidance on testing strategies, it does cover three different stages in the life cycle of fish, including the early stages. Therefore the results are considered to give sufficient evidence as to the chronic effects that are observed in fish. No data are available for chronic toxicity to aquatic invertebrates.
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