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EC number: 204-876-7 | CAS number: 128-04-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Sodium dimethyldithiocarbamate is readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Two GLP studies are available, in which the ready biodegradability of sodium dimethyldithiocarbamate (CAS No. 128-04-1) was assessed according to OECD guidelines 301 D and 301 B, respectively.
In the study according to OECD guideline 301 D, the test item at a concentration of 1.0 and 2.0 mg a.i./L was incubated with activated sludge (predominantly domestic) at 20 ± 2 °C for 28 d. Biodegradation was followed as percentage BOD (biological oxygen demand), relative to the theoretical oxygen demand (ThOD). However, due to the fact that the test item may have selectively inhibited the nitrifying activity of microorganisms, it was considered more appropriate to express results as % ThODNH3. After 28 d, biodegradation values reached 67.7% and 67.3% (1 and 2 mg/L concentrations, respectively). Therefore, it was concluded that sodium dimethyldithiocarbamate is readily biodegradable according to OECD criteria.
In the study according to OECD 301 B 50.0 mg/L test item was inoculated with activated sludge (predominantly domestic) at 22 ± 2 °C for 28 d. A functional and toxicity control was run in parallel. Biodegradation was followed as CO2 production by the respiration of bacteria and expressed as percentage measured CO2 to the theoretical CO2 production (ThCO2). After 28 d, the mean biodegradation of the test item was 80%. All test item replicates had reached the 60% pass level by day 21. The degradation phase (degradation ≥ 10%) had been reached within 9 days. However, the 10-d window was only met by four out of six replicates, and was only marginally missed for the mean of replicates. The percentage degradation of the functional control reached the pass level of ≥ 60% within 8 d and peaked at 92% after 28 d thus confirming the suitability of the test system. The toxicity control reached a biodegradation of 67% within 14 d and 80% after 28 d. Thus, it can be concluded that the test item did not inhibit the biodegradation of the reference item. The substance is considered to be readily biodegradable, but failing 10-day window based on the result of this study.
In conclusion, sodium dimethyldithiocarbamate (CAS No. 128-04-1) is readily biodegradable according to OECD guideline criteria.
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