Registration Dossier
Registration Dossier
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EC number: 205-443-5 | CAS number: 140-93-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- No analysis has been performed and it should be noted in some publications that analysis was not possible due to an absence of the test material. It is expected that the substance will rapidly hydrolyse to the respective alcohols and carbon disulphide.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Ictalurus punctatus
- Details on test organisms:
- SPECIES #
(NAME): 20 Ictalurus punctatus (Channel Catfish)
AGE: NR NR
LIFE STAGE: not reported, unknown
COMMENT: 1.1 G - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 272 mg/L CaCO3
- Test temperature:
- 15 0C
- pH:
- 7.4
- Dissolved oxygen:
- NR
- Salinity:
- SALINITY:NR
- Nominal and measured concentrations:
- TEST CONCENTRATION
CHEM ANAL. METHOD: not reported
UNIT OF MEASURE: AI mg/L active ingredient milligram per Liter
TYPE VALUE RANGE STANDARD CONC (ug/L) ION
A 10 NR TO NR 10000 ug/L NR - Details on test conditions:
- TEST CONDITIONS
STUDY TYPE:
MEDIA: FW (Fresh water)
LOCATION: LAB (Laboratory, indoor)
CONTROL: C (Concurrent control)
EXPOSURE TYPE: S ( static),
APPLICATION FREQ.: 1 X
EXPOSURE DUR.: 96 hour(s),72 hour(s)
STAND DUR. (D): 4 day(s,3 day(s
TEST CONCENTRATION
CHEM ANAL. METHOD: not reported
UNIT OF MEASURE: AI mg/L active ingredient milligram per Liter
TYPE VALUE RANGE STANDARD CONC (ug/L) ION
A 10 NR TO NR 10000 ug/L NR
WATER QUALITY VALUE RANGE (UNIT)
TEMPERATURE: 15 NR TO NR C
pH: 7.4 NR TO NR
HARDNESS: 272 NR TO NR mg/L CaCO3
SALINITY: NR NR TO NR
ALKALINITY: NR NR TO NR NR
CONDUCTIVITY: NR NR TO NR NR
DISSOLVED OXYGEN: NR NR TO NR NR
ORGANIC CARBON (NR): NR NR TO NR NR - Reference substance (positive control):
- not specified
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- EFFECT RESULTS
EFFECT: Mortality
TREND: INC
RESPONSE SITE:NR
% EFFECT: NR
EFFECT MEASUREMENT: Mortality
ENDPOINT
ENDPOINT: Lethal concentration to 50% of test organisms
ENDPOINT ASSIGN.: P (Publication reported endpoint)
SIGNIFICANCE: NA
LEVEL: NA
BCF Value (A): NR ( NR to NR) - Validity criteria fulfilled:
- not specified
- Conclusions:
- Toxicity is in the range expected when considering other tests on the same substance
Certain details lacking, but considered suitable for classification - Executive summary:
Study provided as part of a weight of evidence demonstrating moderate toxicity
No analysis has been performed and it should be noted in some publications that analysis was not possible due to an absence of the test material. It is expected that the substance will rapidly hydrolyse to the respective alcohols and carbon disulphide.- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- No analysis has been performed and it should be noted in some publications that analysis was not possible due to an absence of the test material. It is expected that the substance will rapidly hydrolyse to the respective alcohols and carbon disulphide.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Lepomis macrochirus
- Details on test organisms:
- SPECIES #
(NAME): 2 Lepomis macrochirus (Bluegill)
AGE: NR NR
LIFE STAGE: not reported, unknown
COMMENT: 0.6G - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 272 mg/L CaCO3
- Test temperature:
- 15 0C
- pH:
- 7.4
- Nominal and measured concentrations:
- TEST CONCENTRATION
CHEM ANAL. METHOD: not reported
UNIT OF MEASURE: AI mg/L active ingredient milligram per Liter
TYPE VALUE RANGE STANDARD CONC (ug/L) ION
A 10 NR TO NR 10000 ug/L NR - Details on test conditions:
- TEST CONDITIONS
STUDY TYPE:
MEDIA: FW (Fresh water)
LOCATION: LAB (Laboratory, indoor)
CONTROL: C (Concurrent control)
EXPOSURE TYPE: S ( static),
APPLICATION FREQ.: 1 X
EXPOSURE DUR.: 96 hour(s),72 hour(s)
STAND DUR. (D): 4 day(s,3 day(s
TEST CONCENTRATION
CHEM ANAL. METHOD: not reported
UNIT OF MEASURE: AI mg/L active ingredient milligram per Liter
TYPE VALUE RANGE STANDARD CONC (ug/L) ION
A 10 NR TO NR 10000 ug/L NR
WATER QUALITY VALUE RANGE (UNIT)
TEMPERATURE: 15 NR TO NR C
pH: 7.4 NR TO NR
HARDNESS: 272 NR TO NR mg/L CaCO3
SALINITY: NR NR TO NR
ALKALINITY: NR NR TO NR NR
CONDUCTIVITY: NR NR TO NR NR
DISSOLVED OXYGEN: NR NR TO NR NR
ORGANIC CARBON (NR): NR NR TO NR NR - Reference substance (positive control):
- not specified
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- EFFECT RESULTS
EFFECT: Mortality
TREND: INC
RESPONSE SITE:NR
% EFFECT: NR
EFFECT MEASUREMENT: Mortality
ENDPOINT
ENDPOINT: Lethal concentration to 50% of test organisms
ENDPOINT ASSIGN.: P (Publication reported endpoint)
SIGNIFICANCE: NA
LEVEL: NA
BCF Value (A): NR ( NR to NR) - Validity criteria fulfilled:
- not specified
- Conclusions:
- Toxicity is in the range expected when considering other tests on the same substance
Certain details lacking, but considered suitable for classification - Executive summary:
Study provided as part of a weight of evidence demonstrating moderate toxicity
No analysis has been performed and it should be noted in some publications that analysis was not possible due to an absence of the test material. It is expected that the substance will rapidly hydrolyse to the respective alcohols and carbon disulphide.
Referenceopen allclose all
Description of key information
A number of fish studies have been reviewed and all demonstrate an LC50 in the range of 10 - 100 mg/l giving a reasonable weight of evidence for classification
The more reliable of these sources, and cited by other organisations, is LC50 10 mg/l
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- 10 mg/L
Additional information
The listed toxicity on fish of different xanthates indicate that potassium ethyl xanthate (CAS# 140-89-6) is much more toxic than sodium ethyl xanthate (CSA# 140-90-9) and toxicity of the latest one is not much higher than sodium isopropyl xanthate. The toxicity decrease sharply with increasing temperature.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
