Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: study report data does not give sufficient experimental details

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1963
Report date:
1963

Materials and methods

Type of study / information:
skin irritating study with human volunteers
Endpoint addressed:
skin irritation / corrosion
Principles of method if other than guideline:
other: skin irritating study with human volunteers
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N-isopropyl-N'-phenyl-p-phenylenediamine
EC Number:
202-969-7
EC Name:
N-isopropyl-N'-phenyl-p-phenylenediamine
Cas Number:
101-72-4
Molecular formula:
C15H18N2
IUPAC Name:
N1-phenyl-N4-(propan-2-yl)benzene-1,4-diamine

Results and discussion

Results:
not irritating to slightly irritating

Any other information on results incl. tables

The material was purchased from different companies and
tested on the forearm of 6 subjects for 4 hours (no further
information). Dependent on the material the result was not
irritating to slightly irritating.

Applicant's summary and conclusion