Registration Dossier
Registration Dossier
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EC number: 203-103-0 | CAS number: 103-34-4
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
N,N'-dithiodimorpholine is hydrolitically unstable in water in the pH range 4 to 9. Half-life is inferior to one day at all tested pH. The main metabolite is morpholine.
Key value for chemical safety assessment
Additional information
N,N'-dithiomorpholine hydrolysis was studied according to a GLP OECD 111 study (Chastenet, 2014). At pH 1.2 and 37°C, half-life was inferior to 30 min. At pH 4 and 25°C, half-life was inferior to 1 hour. At pH 7 and 25°C, half life was around 3 hours. At pH 9 and 25°C, half-life was aroung 20 hours. N,N'-dithiodimorpholine mainly degrades in morpholine on the one hand and probably sulfure on the other hand, although sulfure was not seen by chromatography.
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