Registration Dossier
Registration Dossier
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EC number: 310-290-3 | CAS number: 161907-80-8
Endpoint summary
Administrative data
Description of key information
Additional information
The environmental hazard assessment for (fresh-) water organisms and sediment habitats is supported by several acute studies (pelagic compartment) and by using scientific argumentation (sediment dwelling organisms).
The above studies were conducted with B-TTEGME containing mixtures. These test materials, i.e., methyl borated esters and brake fluids, contained 44 and 35% B-TTEGME, respectively. The tests were conducted up to 1000 mg test material/L, corresponding to 350 and 440 mg B-TTEGME/L. For the assessment of these studies it is assumed that neither synergistic nor antagonistic effects influence the toxicity of B-TTEGME and - as worst case scenario - the toxicity observed for the mixture is only due to the toxicity of B-TTEGME. The concentration of B-TTEGME in the respective mixtures was used to calculate the effect concentrations for B-TTEGME.
The (acute) LC50 and EC50 values for (freshwater) fish, daphnids algae were >444.8, >422.4 and >448.8 mg B-TTEGME/L. The EC50 for STP microorganisms was > 1000 mg B-TTEGME/L.
Experimental information about toxicity on marine organisms is not available.
Based on the facts that B-TTEGME is ready biodegradable, hydrolyses quickly, has a log Pow of << 3, has a low Koc resulting in a low likelihood to partition to sediment and is not toxic to pelagic aquatic organisms, B-TTEGME is not expected to cause adverse effects on sediment organisms and consequently sediment toxicity tests do not need to be conducted to assess the risk for sediment-dwelling organisms.
Experimental results and scientific assessments indicate that Daphnia magna was the most sensitive species of the aquatic compartment with an EC50 of > 422.4 mg B-TTEGME/L. Hence, the most conservative, worst case endpoint for the freshwater aquatic environment is 422.4 mg B-TTEGME/L. This value will be used for the CSA. This value is higher than the limit for classification and labeling, i. e., higher than 100 mg B-TTEGME/L.
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