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EC number: 214-275-1
CAS number: 1119-34-2
Information on environmental fate and pathyways, in particular on
biodegradation, is deduced by read-across from studies for L-arginine.
L-arginine-HCl as such is not a natural constituent of peptides
and proteins. L-arginine-HCL is the salt resulting from the reaction of
the basic L-arginine with HCl. Due to is higher water solubility
L-arginine-HCl is often preferably applied than L-arginine, in
particular when bioavailability is desired property for the intended use.
L-arginine-HCl dissociates in aqueous solution to ionic L-arginine
as well as H+and Cl-. The inorganic ions resulting
from physiological concentrations are not of concern for toxicokinetics
as the “background” concentration in the body is by magnitudes higher
In a GLP-guideline study L-arginine showed 100% degradation after 28
days and therefore can be considered as readily biodegradable. Thus,
L-arginine-HCl can be considered as readily biodegradable, too.
studies are waived in accordance with REACH.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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