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Long-term toxicity to aquatic invertebrates

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Description of key information

NOECrepro (23 d) 7.8 µg/L D. magna (based on read-across from pentadecan-1-ol)

Key value for chemical safety assessment

Additional information

A 23 days NOECrepro value of 7.8 µg/L has been determined for the effects of pentadecan-1 -ol on cumulative number of offsprings of the freshwater invertebrate D. magna. This is the lowest reliable value available for this endpoint and has been selected as key.

A study report is available with the closely related substance pentadecanol branched (a single methyl branch group in the 2-position).This type of branched structure is termed 'essentially linear' and the physicochemical, toxicological and ecotoxicological properties and behaviour do not differ significantly between such structures and their linear analogues. It is therefore possible to read-across between the two substances. Additionally these isomeric substances have an identical molecular weight. The difference in composition is dependent on the manufacturing process which may create linear alcohols or simple mono-branched structures. Direct read-across from pentadecanol branched to pentadecanol (CAS 629-76-5) is scientifically justified.

A reliable 21 d NOEC(reproduction) value of 30.2 ug a.i./L has been determined for the effects of pentadecanol branched on the number of reproductive young produced per day of the freshwater cladoceran Daphnia magna. The water solubility of pentadecanol branched has been estimated to be 0.07 mg/L. Therefore the NOEC is >limit of solubility (>LoS).